C-Fibers: Small in Diameter, Multifaceted in Function

Monday, September 19th
8:30am12:00pm EDT

About the Session


  • Lars Arendt-Nielsen, Dr.med. et lic.techn.; Professor (Denmark)
  • Leigh Nattkemper, PhD (USA)
  • Martin Schmelz, MD; professor (Germany)
  • Manon Sendel, MD (Germany)

C-Fibers play a large role in neuropathic pain conditions. Understanding their function can aid tremendously in understanding different symptoms of neuropathy and therapeutic approaches. This workshop will demonstrate different functions of C-fibers taking into consideration not only pain but also itch.

Participants will get an introduction to the different methods used in pain and itch research with an emphasis on allodynia and hyperalgesia as well as alloknesis and hyperknesis accordingly. This may not only further the understanding of the methodology behind recent studies, but can also give an impression of symptoms experienced by patients and the mechanisms behind them. The capsain model, the histamine model and C-fiber specific electrostimulation can be experienced first hand. Furthermore, it will be shown, how the different models are implemented and how to best assess the subject the model was used on.