Friday, September 23rd
10:45am-12:15pm EDT


Topical Workshop


Evidence - clinical trials - systematic review - guidelines - implementation science | Evidence, clinical trials, systematic review, guidelines and implementation science


716 B

Modifiable Contributors to Initiation of Misuse of Prescription Opioids for Acute Pain During Adolescence

Adolescence is a vulnerable period when individuals are susceptible to the development of pain and substance use disorders. Opioid misuse often begins in adolescence, with rates peaking in early adulthood (7.8% of 18-25 year olds misuse opioids). Opioids prescribed for pain are a major driver of adolescent opioid misuse, with over 17% of adolescents in the US receiving an opioid prescription to each year. Indeed, adolescents report physical pain as the primary motivation for misuse. Nevertheless, opioids remain the cornerstone of acute moderate-severe pain management. Limited data are available to understand the intersection of acute pain and opioid misuse in adolescents, to inform prevention approaches. Qualitative data from a mixed clinical sample of adolescents who recently experienced injury, surgery, or critical illness, will be presented to provide insight into adolescents’ perceptions about use and misuse of prescription pain medicines which may influence risk for developing use disorders. Current work examining psychosocial factors, pain relief preferences, and expectancies as risk factors for opioid misuse following spinal fusion surgery in a large, well characterized, previously opioid-naive sample of adolescents enrolled an ongoing RCT will be discussed. Findings will identify targets for intervention to reduce lifetime burden of resulting opioid use disorders.


Dr. Jennifer A. Rabbitts

Associate Professor
University of Washington