Wednesday, September 21st
Imaging: Pain Imaging and Neuroimaging
Peak Alpha Frequency as a Potential Biomarker of Chronic Neuropathic Pain with Some Sex Specificity
The Davis lab has identified abnormalities in alpha oscillations within the dynamic pain connectome across multiple chronic pain conditions, including multiple sclerosis, ankylosing spondylitis, and neuropathic pains. The speaker will describe the findings that point to deficits in alpha activity that include the speed (i.e., alpha slowing) and power of the peak alpha frequency (PAF) as well as abnormal synchrony (i.e., functional coupling or functional connectivity) at alpha frequencies that normally occur between regions of the dynamic pain connectome. The speaker will also highlight the data that support the proposition that PAF is a biomarker of chronic neuropathic pain as well as data that point to sex-specificity of certain findings.