Quality, Bias, and Integrity in Pain Research: Creating the Next Generation of Pain Science

Monday, September 19th
1:00pm4:30pm EDT

About the Session

Methodology, Evidence Synthesis, and Implementation SIG Symposium

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Systematic review has highlighted how poor quality and biased primary studies can lead to misleading claims for efficacy and safety in treatment. Further investigations into two serious aspects of research integrity – fraud and spin – have led to a renewed interest in methods for ensuring the quality and trustworthiness of modern pain research.

Learning Objectives:

In this symposium we will report on:

  1. How to understand quality in both primary research and systematic review
  2. How spin and diversion occur
  3. How research misconduct can occur and its effects on the literature

A discussion will then be had on how to ensure that the next generation of pain studies can guarantee the highest integrity possible.



13:00 – Symposium Begins

13:00-13:05 – Chris Eccleston (UK): Opening Remarks

13:05-13:35 – Andrew Moore (UK): Quality and Bias in Clinical Pain Science

13:35-14:05 – Emma Fisher (UK): Research Integrity I: Spin and Diversion in Pain Science

14:05-14:35 – Michael Merraro (Australia): Research Integrity II: Retraction and its causes in pain science with

14:35-14:50 – Afternoon Coffee Break

14:50-15:20 – Neil O’Connell (UK): Research Integrity III: Exploring divergent results through an integrity lens

15:30-16:15 – Fireside discussion and debate. On building labs with integrity, the roles of the editor, and lessons for training:

  • Amanda C de C Williams (UK)
  • Tonya Palermo (US)
  • Neil O’Connell (UK)
  • Chaired by Emma Fisher (UK)

16:15-16:25 – Sebastian Straube (Canada): Reflections, and practical strategies to develop cultures of integrity

16:25 – Chris Eccleston (UK): Closing Remarks

16:30 – End of Symposium